تالیفات

 

APLAR EVALUATION OF BEHCET'S DISEASE DIAGNOSTIC CRITERIA.

Authers: Y. Dong, G. Yao, F. Davatchi, F. Shahram, M. Akbarian, S. Lee, D. Bang, E. Lee.

Abstract: INTRODUCTION: There are six sets of diagnosis criteria for Behcet's Disease (BD). There is yet no general agreement on which one to use. The International criteria was created to bring this agreement. The aim of this study was to evaluate these criteria, especially the performance of the International criteria. MATERIALS and METHODS: Three countries (China, Iran and Korea) participated in the study. In each country, BD patients were selected as every ... سال انتشار: 1998
 

Azathioprine for The Treatment of Ophthalmological Lesions of Behcet’s Disease.

Authers: F. Davatchi, F. Shahram, H. Chams, M. Akbarian, A. Nadji, C. Chams, F. Gharibdoost, A. Jamshidi, S. Soroosh

Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) are the main morbidity factor in Behcet’s Disease (BD). They usually progress toward severe loss of vision or blindness. They need aggressive treatment with cytotoxic drugs. Azathioprine was demonstrated, in a double blind control study, to be effective in Behcet’s Disease. The aim of this study was to evaluate the efficacy of Azathioprine in ocular lesions of BD, and to compare ... سال انتشار: 1998
 

Bone Mass Density in Normal Iranian Population.

Authers: M. Akbarian, F. Davatchi, A. Salimzadeh, F. Shahram, F. Gharibdoost, A. Nadji, M. Pajouhi, A. Jamshidi

Abstract: The bone mass density (BMD) may vary in different countries due to different genetic and environmental factors. This study was performed to determine the BMD of the normal population in Iran. Subjects were selected randomly from different social workers classes in Tehran (from the lowest to the highest). For each decade and sexes, 20 normal subjects were selected (140 men and 140 women). BMD was measured with a Hologic 1000 ... سال انتشار: 1998
 

Cardiac Involvement in Behcet's disease, a case control study.

Authers: F. Shahram, M. Eslami, B. Shakoori, M. Haydari, A. Nadji, M. Akbarian, F. Davatchi

Abstract: Introduction: Behcet's disease (BD) is a multisystem disease characterized by recurrent oral and genital ulcers, skin and ocular lesions. Other organ involvement occurs as minor manifestations of the disease. Cardiac involvement is not a common feature of the disease, but may be a sign for poor prognosis. The exact prevalence of cardiac involvement is not exactly known, only selected cases are reported in the literature. Our study .was designed to ... سال انتشار: 1998
 

Combination Therapy with Low Dose Pulse Cyclophosphamide and Methotrexate in Ocular Lesions of Behcet’s Disease.

Authers: F. Shahram, H. Chams, F. Davatchi, A. Nadji, M. Akbarian

Abstract: Introduction: Cytotoxic drugs are all effective in the treatment of ocular lesions of Behcet’s disease (BD). However, with all methods there are some patients that their eye lesions will progress despite the treatment. This study was designed to find whether a combination therapy with 2 of these drugs could have better effect in reducing the rate of non-responders. Materials & Methods: Twenty eight patients diagnosed as BD (according to the Iran ... سال انتشار: 1998
 

Comparison of Juvenile wth Adult Behcet’s Disease.

Authers: N. Shafaei, F. Shahram, F. Davatch, A. Nadji, M. Akbarian, F. Gharibdoost, S. Soroosh

Abstract: Introduction: Behcet’s disease (BD) is not rare in children. Its clinical picture differs from adults. The purpose of this study was 1-To find the characteristics of juvenile BD (JBD). 2-To compare JBD with the adult from (ABD) of the disease. Materials & Methods: In a cohort of 3729 patients with BD, different manifestations of the disease, including 100 clinical and paraclinical data, were analyzed. Patients were divided in two groups. 1- ... سال انتشار: 1998
 

OVERLAP IN CONNECTIVE TISSUE DISEASES EVALUATION OF 119 CASES.

Authers: S.G. Soroosh, F. Shahram, M. Akbarian, F. Gharibdoost, A. Nadji, A. Jamshidi, F. Davatchi

Abstract: The overlap syndrome is a vague entity in the group of connective tissue diseases. It is unclear whether it is fortuitous association of two or more connective tissue diseases (CTD), or a distinct disease. The early description of this syndrome was "a collection symptoms of CTD and the existence of anti - nRNP antibody". Many studies however, show that the anti - nRNP antibody is not specific for diagnosis. The ... سال انتشار: 1998
 

Epidemiology Of Behcet’s Disease In Middle East And Asia.

Authers: F. Davatchi

Abstract: Historical Background: Behcet's Disease (BD) is mainly seen along the Silk Rout This very peculiar geographical distribution arises the question that weather the disease was spread from east to west or from west to east. The epidemiology of BD in Iran shows that the genetic background is related to the East Asians (Mongoloid) race. This finding suggests that BD was spread along the Silk Route from East to ... سال انتشار: 1998
 

Epidemiology of Behcet's disease in Iran.

Authers: F. Davatchi, F. Shahram, C. Chams, H. Chams, M. Akbarian, F. Gharibdoost, A. Nadji, A. Jamshidi, S. Soroosh

Abstract: Introduction: The geographical distribution of Behcet's Disease (B.D) is thought to be due to the predisposing factor(s) spread along the Silk Route. It is widely accepted that the predisposing factor(s) is of genetic origin. However the rarity of BD among Hawaiian's Japanese immigrants may be in favor of environmental factors. Iran is situated in the middle of the Silk Route. Caucasians account for 75.4%, Turks (from Mongoloid ethnic origin) for ... سال انتشار: 1998
 

Familial Oral Aphthosis in General Population As Compared To Behcet’s Disease.

Authers: C. Chams, F. Davatchi, F. Shahram, M. Akbarian, A. Nadji, F. Gharibdoost, H. Chams, A. Jamshidi.

Abstract: Introduction: Oral aphthosis (OA) is seen in 96% of patient with Behcet’s Disease (BB) OA is said to be rather frequent in the general population. It was therefore interesting to determine whether OA in the general population had also a genetic background as it is for BD. It was also interesting to determine if the genetic background was similar in both conditions (BD and OA in the general population). Therefore, ... سال انتشار: 1998
 

Familial Study in Behcet's Disease, Analysis of 1242 Patients.

Authers: F. Shahram, C. Chams, F. Davatchi, A. Nadji, M. Akbarian. A. Jamshidi

Abstract: Introduction: The etiology of Behcet's disease (BD) is unknown, but like other autoimmune disorders both environmental and genetic factors contribute to its pathophysiology. The familial form of BD is in favor of a genetic predisposition. This study was designed to evaluate the prevalence of the familial form and their possible effect on the disease expression in Iranian patients. Materials & Methods: We studied prospectively 1242 consecutive patients with ... سال انتشار: 1998
 

Iconography Of Non Classic Muco-cutaneous Lesions Of Behcet’s Disease.

Authers: F. Davatchi, C. Chams.

Abstract: Introduction: Mucous membrane manifestations of Behcet's Disease (BD) are the most important and frequent lesions of the disease. The classic lesions are well known. Other forms exist that are not given usually enough attention. Mucous Membrane Manifestations: The classical lesions are the oral and the genital aphthosis. 0ther forms are: 1- Rare forms of oral aphthosis: a/- ­Punctiform aphthous lesions: They are small and difficult to see. b/- The miliaria aphthosis: It ... سال انتشار: 1998
 

Juvenile Behcet's Disease: Diagnosed Before Or After Childhood?

Authers: F. Shahram, N. Shafaie, F. Davatchi, A. Nadji, M. Akbarian, A. Jamshidi

Abstract: Introduction: Behcet's disease (BD) is underdiagnosed in children. It is mainly due to the wide range manifestations of the disease, the low specificity of the symptoms, and the unfamiliarity of most physicians with childhood BD. These patients are not included in the juvenile group and may be a cause of controversy in the description of BD in children. The aim of this study was to find if the characteristics of ... سال انتشار: 1998
 

Methotrexate in the Treatment of Ocular Lesions of Behcet’s Disease in Children.

Authers: N. Shafaie, F. Shahram, H. Chams, F. Davatchi, A. Nadji, M. Akbarian

Abstract: Introduction: Different methods of treatment were employed in ocular lesions of Behcet’s disease (BD) in adults. Most of them are not permitted in children due to their potential toxicity. Methotrexate (MTX) has gained wide acceptance for the treatment of childhood rheumatic diseases. On the other hand, we showed in several reports the efficacy of MTX in the treatment of ocular lesions of BD. This study was designed to show the ... سال انتشار: 1998
 

METHOTREXATE FOR OCULAR LESIONS OF BEHCET'S DISEASE. COHORT STUDY ON 262 PATIENTS.

Authers: F. Davatchi, F. Shahram, H. Chams. M. Akbarian, A. Nadji. F. Gharibdoost, C. Chams. A. Jamshidi, S. Soroosh

Abstract: INTRODUCTION: Ocular lesions of Behcet's Disease (BD) progress usually toward severe loss of vision or blindness, if not aggressively treated. Cytotoxic drugs are the main therapeutic arsenals used for it: Low dose methotrexate (MTX) by its safety and its efficacy is one of the best therapeutic choices. MATERIALS &METHODS: MTX was used as 7.5 mg weekly. Prednisolone was associated as 0.5 mg/kg/ daily. Upon the suppression of the inflammatory reaction, prednisolone ... سال انتشار: 1998
 

Pulse Cyclophosphamide for ocular Manifestations of Behcet's Disease. Cohort study on 283 patients.

Authers: F. Davatchi, F. Shahram, H. Chams, M. Akbarian, A. Nadji, F. Gharibdoost , A. Jamshidi

Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) usually progress toward severe loss of vision or blindness, if not aggressively treated. The aim of this study is to evaluate the efficacy of Pulse Cyclophosphamide (PCP) in a cohort study. Methods: This study includes all patients treated with PCP from 1986 to 1998, for active PU and or RV. PCP was administered as Ig cvclophosphamide/m2/body surface, once per month. Prednisolone was given ... سال انتشار: 1998
 

The comparison of Clinical Manifestations between Scleroderma and overlap Syndrome (Polymyositis with Scleroderma).

Authers: F. Gharibdoost, A. Nadji, M. Akbarian, F. Shahram, A. Jamshidi, F. Davatchi

Abstract: The objective of this study was to compare the clinical manifestations of scleroderma(Scl) and overlap syndrome(Scl/PM). Seventy four patients with thirty five months symptoms duration of scleroderma (sixty five women, nine men) and fifteen with thirty two months symptoms duration of overlap (nine women , six men) were studied over a period of 8 years. The mean age at the disease onset was 31.8 years in Scl and 31.6 years ... سال انتشار: 1998
 

Vascular Involvement In Behcet’s Disease: Report Of 323 Cases.

Authers: A. Nadji, F. Shahram, F. Davatchi, M. Akbarian, F. Gharibdoost, A. Jamshidi

Abstract: Introduction: Vascular involvement, as a hallmark of Behcet’s disease (BD), involves arteries and veins of all size and may be a poor prognostic sign. Like the other manifestations of the disease, its prevalence varies widely according to the reports from different parts of the world (7.7 to 60%). The difference may be due to ethic variation or environmental factors. The aim of this study is to find the characteristics of ... سال انتشار: 1998
 

Vasculitis in Ocular Lesions Of Behcet’s Disease, Impact on Outcome.

Authers: H. Chams, F. Shahram, F. Davatchi, A. Nadji, M. Akbarian, C. Chams

Abstract: Introduction: Ocular lesions are the leading cause of morbidity in Behcet’s disease (BD). Many factors contribute to the loss of vision in BD, as uveitis, retinal vasculitis, and their secondary complications such as cataract, hemorrhage, vessel necrosis, neovascularization, optic atrophy, etc. The purpose of this study was to determine the impact of retinal vasculitis on the evaluation of ocular Behcet’s (OB) and its outcome after an early or late treatment. Materials & ... سال انتشار: 1998