تالیفات

Influence of HLA-B27 Subtypes on Ankylosing Spondylitis Phenotype: Comment on the Article by Akassou et al  

Influence of HLA-B27 Subtypes on Ankylosing Spondylitis Phenotype: Comment on the Article by Akassou et al

مولف: Sasan Fallahi1, 2

خلاصه: To the Editor I read the interesting review of Akassou and Bakri about the influence of HLA-B27 on ankylosing spondylitis (AS) phenotype which has been recently published in Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders.1 They concluded in the last row of Table 2, “Fallahi et al found lower markers of activity, better functional status, better quality of life and better spinal and hip mobility in patients with B*2704 and B*2707 compared with patients with B*2705 and B*2702 ... سال انتشار: 2018
 

Effect of HLA-B*27 and its Subtypes on Clinical Manifestations and Severity of Ankylosing Spondylitis in Iranian Patients

Authers: Sasan Fallahi1, 2, Mahdi Mahmoudi2, Mohammad Hossein Nicknam3, 5, Farhad Gharibdoost2, Elham Farhadi4, Azad Saei5, Keramat Nourijelyani6, Nooshin Ahmadzadeh2, and Ahmad Reza Jamshidi2

Abstract: The aim of this study was to assess the role of HLA-B*27 and it’s subtypes in determining severity and clinical manifestations of ankylosing spondylitis (AS). A total of 163 AS patients were assessed for clinical manifestations and severity using structured questionnaires. HLA-B*27 screening and B*27 sub-typing were performed by PCR. One hundred twenty two patients (74.8%) were B*27 positive. The male to female ratio, peripheral arthritis, steroid use, intense dorsal kyphosis and ... سال انتشار: 2013