تالیفات

Influence of HLA-B27 Subtypes on Ankylosing Spondylitis Phenotype: Comment on the Article by Akassou et al  

Influence of HLA-B27 Subtypes on Ankylosing Spondylitis Phenotype: Comment on the Article by Akassou et al

مولف: Sasan Fallahi1, 2

خلاصه: To the Editor I read the interesting review of Akassou and Bakri about the influence of HLA-B27 on ankylosing spondylitis (AS) phenotype which has been recently published in Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders.1 They concluded in the last row of Table 2, “Fallahi et al found lower markers of activity, better functional status, better quality of life and better spinal and hip mobility in patients with B*2704 and B*2707 compared with patients with B*2705 and B*2702 ... سال انتشار: 2018
 

Gender differences in Iranian patients with ankylosing spondylitis

Authers: Abtin Shahlaee & Mahdi Mahmoudi & Mohammad Hossein Nicknam & Elham Farhadi & Sasan Fallahi & Ahmad Reza Jamshidi

Abstract: Abstract Inequalities in features and severity of ankylosing spondylitis (AS) have been noticed between men and women, suggesting a possible influence of gender on disease phenotypes. Comparing disease features and characterization of gender differences in clinical features and medications could help elucidate the potential influence of gender on the severity of AS in patients. This study aims to assess the influence of gender on disease patterns in Iranian patients with AS. Three hundred and twenty patients diagnosed with ... سال انتشار: 2015
 

Are clinical measures influenced by various ethnic origins in Iranian patients with ankylosing spondylitis? A pilot study

Authers: Sasan Fallahi (MD) * 1, 2 Ahmad Reza Jamshidi (MD) 2 Mahdi Mahmoudi (MD) 2 Mostafa Qorbani (MD)

Abstract: Abstract Background: Ankylosing spondylitis (AS) may manifest with heterogeneous patterns according to ethnic origins. The purpose of this study was to describe the influence of various Iranian ethnic origins on clinical measures in patients with AS. Methods: 0ne hundred sixty-three AS patients diagnosed by modified New York 1984 criteria were enrolled consecutively. The patients were classified into Fars, Turk, Kord, Lor and other ethnic origins. Several clinical measures were described and compared ... سال انتشار: 2014
 

The Correlation between Pack-Years of Smoking and Disease Activity, Quality of Life, Spinal Mobility, and Sacroiliitis Grading in Patients with Ankylosing Spondylitis

Authers: Sasan FALLAHI, 1, 2 Ahmad Reza JAMSHIDI, 2 Farhad GHARIBDOOST, 2 Mahdi MAHMOUDI, 2 Nooshin AHMADZADEH, 2 Mohammad Hossein NICKNAM3

Abstract: This study aims to investigate the correlation between the pack-years of smoking and disease activity, quality of life, spinal mobility, and sacroiliitis grading and ankylosing spondylitis (AS) in Iranian patients with AS. Patients and methods: A total of 160 AS patients were evaluated according to their smoking status and pack-years of smoking. The outcome measures were disease activity, quality of life, spinal mobility, and sacroiliitis grading, and these were assessed by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), ... سال انتشار: 2013
 

Effect of HLA-B*27 and its Subtypes on Clinical Manifestations and Severity of Ankylosing Spondylitis in Iranian Patients

Authers: Sasan Fallahi1, 2, Mahdi Mahmoudi2, Mohammad Hossein Nicknam3, 5, Farhad Gharibdoost2, Elham Farhadi4, Azad Saei5, Keramat Nourijelyani6, Nooshin Ahmadzadeh2, and Ahmad Reza Jamshidi2

Abstract: The aim of this study was to assess the role of HLA-B*27 and it’s subtypes in determining severity and clinical manifestations of ankylosing spondylitis (AS). A total of 163 AS patients were assessed for clinical manifestations and severity using structured questionnaires. HLA-B*27 screening and B*27 sub-typing were performed by PCR. One hundred twenty two patients (74.8%) were B*27 positive. The male to female ratio, peripheral arthritis, steroid use, intense dorsal kyphosis and ... سال انتشار: 2013
 

Katayoon Bidad • Sasan Fallahi • Mahdi Mahmoudi • Ahmadreza Jamshidi • Elham Farhadi • Alipasha Meysamie • Mohammad Hossein Nicknam

Authers: Katayoon Bidad • Sasan Fallahi • Mahdi Mahmoudi • Ahmadreza Jamshidi • Elham Farhadi • Alipasha Meysamie • Mohammad Hossein Nicknam

Abstract: The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) are widely used instruments in assessment of patients suffering from ankylosing spondylitis (AS). The Patient Acceptable Symptom State (PASS) is regarded as a target for patients’ well-being. The aim of this study was to translate and adapt BASDAI, BASFI and PASS into the Iranian official language, Farsi, and evaluate their reliability and validity. Ninety patients with AS were included in this study. The ... سال انتشار: 2012
 

Association between Endoplasmic Reticulum Aminopeptidase-1 (ERAP-1) and Susceptibility to Ankylosing Spondylitis in Iran

Authers: Mahdi Mahmoudi1, 2, 3, Ahmad Reza Jamshidi2, Ali Akbar Amirzargar1, 3, Elham Farhadi1, Keramat Nourijelyani4, Sasan Fallahi2, 5, Mona Oraei3, Sahar Noori4, and Mohammad Hossein Nicknam1, 3

Abstract: Ankylosing Spondylitis (AS) is an inflammatory arthritis, which affects mainly spine and sacroiliac joints. According to recent studies, ERAP1 is the second most common candidate gene for AS susceptibility after HLA-B27. The aim of this study was to determine the association of ERAP1 gene polymorphisms with AS in Iranian population. The study group comprised 387 Iranian AS patients and 316 healthy controls from Iran. Using Real Time PCR allelic discrimination method, we genotyped four SNPs ... سال انتشار: 2012
 

Urolithiasis in ankylosing spondylitis: Correlation with Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI)

Authers: Sasan Fallahi (MD) *1, 2 Ahmad Reza Jamshidi (MD) 2 Farhad Gharibdoost (MD) 2 Mahdi Mahmoudi (PhD) 2 Pedram Paragomi (MD) 2 Mohammad Hossein Nicknam (MD, PhD) 3 Elham Farhadi (MSc) 3 Mostafa Qorbani (PhD) 4

Abstract: Increased incidence of renal stone has been reported in ankylosing spondylitis (AS), but unlike some well-known renal involvements, they have not been fully studied. The aim of this study was to investigate the association of AS with urolithiasis and also the relation between urinary stone and severity markers. Methods: One hundred-sixty three AS patients were included in a cross-sectional study from Iranian AS association, Iran Rheumatology Center and Rheumatology Clinic of ... سال انتشار: 2012
 

Evaluation of the Iranian versions of the bath ankylosing spondylitis disease activity index (BASDAI), the bath ankylosing spondylitis functional index (BASFI) and the patient acceptable symptom state (PASS) in patients with ankylosing spondylitis

Authers: Katayoon Bidad, Sasan Fallahi, Mahdi Mahmoudi, Ahmadreza Jamshidi, Elham Farhadi, Alipasha Meysamie, Mohammad Hossein Nicknam

Abstract: The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) are widely used instruments in assessment of patients suffering from ankylosing spondylitis (AS). The Patient Acceptable Symptom State (PASS) is regarded as a target for patients’ well-being. The aim of this study was to translate and adapt BASDAI, BASFI and PASS into the Iranian official language, Farsi, and evaluate their reliability and validity. Ninety patients with AS were included in this study. The ... سال انتشار: 2011