تالیفات

 

Gene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells of Patients with Systemic Sclerosis

Authers: Simin Almasi, 2Saeed Aslani, 1Hadi Poormoghim, 2Ahmadreza Jamshidi, 2Shiva Poursani and 2Mahdi Mahmoudi

Abstract: The Toll-Like Receptor (TLR) family is appeared to be expressed in many cell types in the immune system and plays a role in the pathogenesis of various autoimmune diseases. The expression profile and role of TLRs in Systemic Sclerosis (SSc) have been partly explained. It is aimed through this investigation to evaluate the expression pattern of TLR 4 and 5 in Peripheral Blood Mononuclear Cells (PBMCs) from SSc patients. PBMCs were isolated from whole blood of ... سال انتشار: 2016
 

Systemic sclerosis: comparison of efficacy of oral cyclophosphamide and azathioprine on skin score and pulmonary involvement—a retrospective study

Authers: Hadi Poormoghim · Nader Rezaei · Zeinab Sheidaie · Ali Reza Almasi · Maziar Moradi‑Lakeh · Simin Almasi · Elham Andalib

Abstract: Abstract T he aim of this study was to evaluate efficacy of azathioprine (AZA) and cyclophosphamide (CYC) as a therapeutic regimen for interstitial lung disease associated with systemic sclerosis (SSc). Thirty-six selected patients included in this retrospective cohort and received one of the two drugs; the first group consists of 15 patients who were treated with AZA (1.5–2 mg/kg/day) and the second group with 21 patients received oral CYC (up to 2 mg/kg/day). Both groups received additional low ... سال انتشار: 2014
 

Isolated Hematuria in SLE Patients and its Association with Proteinuria, Urinary Cast and SLE Disease Activity

Authers: M. Akbarian, H. Soleymani, F. Gharibdoost, A. Nadji, A.R. Jamshidi, , F. Shahram, M. Akhlaghi, S. Khosravi, S. Almasi, Fereydoun Davatchi

Abstract: Isolated hematuria and its association with proteinuria, and urinary cast and systemic lupus erythematosus (SLE) disease activity, and decision for renal biopsy is a dilemma for physician in SLE patients. The aim of this study was to investigate 1. whether isolated hematuria is associated with active SLE, 2. to determine duration between hematuria and proteinuria and urinary cast, and 3. to determine renal histological type in SLE patients with isolated hematuria. All episodes of ... سال انتشار: 2009
 

Assessment of Serum Thrombomodulin in Patients with Systemic Lupus Erythematosus in Rheumatology Research Center

Authers: Mahmood Akbarian, Farhad Gharibdoost, Mehrzad Hadjaliloo, Abdolhadi Nadji, Ahmad Reza Jamshidi, Farhad Shahram, Masoomeh Akhlaghi, Shahrzad Khosravi, Simin Almasi, Fereydoun Davatchi

Abstract: At present, some clinical presentations and serological parameters such as products of complement activation and elevation of autoantibodies (e.g. dsDNA antibodies), erythrocyte sedimentation rate (ESR), levels of C-reactive protein (CRP), or cytokines such as IL-2/IL-2 receptor, IL-6 and IL-10 are used as indirect serological markers with variable degrees of significance. To date, no specific serological parameter is available to assess disease activity in SLE. Soluble serum thrombomodulin is a new marker of endothelial cell injury ... سال انتشار: 2009