تالیفات

 

Effects of intravenous Semelil (ANGIPARSTM) on diabetic foot ulcers healing: A multicenter clinical trial

Authers: Larijani B, Heshmat R, Bahrami A, Delshad H, 5Ranjbar Omrani G, Mohammad K, Heidarpour R, Mohajeri Tehrani MR, Kamali K, Farhadi M, Gharibdoust F, , Madani SH

Abstract: Some diabetic foot ulcers, which are notoriously difficult to cure, are one of the most common health problems in diabetic patients .There are several surgical and medical options which already have been introduced for treatment of diabetic foot ulcers, so some patient will require amputation. The purpose of this study was to evaluate the efficacy of intravenous Semelil (ANGIPARSTM), a naive herbal extract to accelerate healing of diabetic foot ulcers. A multi-centric randomized controlled trial ... سال انتشار: 2008
 

Assessment of maximum tolerated dose of a new herbal drug, Semelil (ANGIPARSTM) in patients with diabetic foot ulcer: A Phase I clinical trial

Authers: Heshmat R, , 1Mohammad K, , 2Mohajeri Tehrani MR, 2Tabatabaie Malazy O, Keshtkar AA, Gharibdoust F, , 2Larijani B

Abstract: Background and the purpose of the study: In many cases of diabetic foot ulcer (DFU) management, wound healing is incomplete, and wound closure and epithelial junctional integrity are rarely achieved. Our aim was to evaluate the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of Semelil (ANGIPARSTM), a new herbal compound for wound treatment in a Phase I clinical trial. Methods: In this open label study, six male diabetic patients with a mean age of ... سال انتشار: 2008