تالیفات

 

Fc-Gamma Receptor 3B Copy Number Variation Is Not a Risk Factor for Behc¸et’sDisease

Authers: Rachel Black, 1 Sue Lester, 1 Emma Dunstan, 1 Farhad Shahram, 2 Abdolhadi Nadji, 2 Noushin Bayat, 2, 3 Kayvan Saeedfar, 2, 4 Naghmeh Ziaei, 2 Catherine Hill, 1, 5 Maureen Rischmueller, 1, 5 and Fereydoun Davatchi2

Abstract: Behc¸et’s disease (BD) is an immune-mediated systemic vasculitis associated with HLAB51. Other gene associations are likely and may provide further insight into the pathogenesis of this disease. Fc-gamma receptors play an important role in regulating immune function. Copy number variation (CNV) of the Fc-gamma receptor 3B (FCGR3B) gene is associated with other inflammatory conditions and may also play a role in BD. The aim of this study was to determine whether CNV of ... سال انتشار: 2012
 

EVALUATION OF IL1- AND TNF- SERUM LEVELS IN RHEUMATOID ARTHRITIS PATIONTS WITH ACTIVE AND INACTIVE, WITH OR WITHOUT BONE EROSION

Authers: A. R. Rostamian*, , A. H. Naji, , F. Gharibdoost, , A. Khalvat, L., Jafari-Saraf, K. Saeedfar

Abstract: Abstract- Rheumatoid arthritis is the most common inflammatory joint disease with 1 percent prevalence in community which presents with symmetrical polyarthritis of hands with inflammatory behavior. Several studies in recent years were conducted for evaluation of inflammatory cytokines such as IL1-& (Interleukin 1&) and TNF- & (Tumor necrosis factor) in rheumatologic disorders including rheumatoid arthritis to find new treatment methods base to pathogenesis. In this study different serum levels of IL1-& and TNF- & in ... سال انتشار: 2007