تالیفات

Genetic diversity of Mycobacterium tuberculosis isolates causing pulmonary and extrapulmonary tuberculosis in the capital of Iran  

Genetic diversity of Mycobacterium tuberculosis isolates causing pulmonary and extrapulmonary tuberculosis in the capital of Iran

مولف: Shima Hadifara, b, 1, Leila Shamkhalia, b, 1, Mansour Kargarpour Kamakolia, b, Shayan Mostafaeic, d, Sharareh Khanipoura, Noormohamad Mansoorie, Abolfazl Fateha, b, Seyed Davar Siadata, b, Farzam Vaziria, b, ⁎

خلاصه: Objectives: Evaluation of the genetic diversity of Mycobacterium tuberculosis (M.tb) and determining if the association between a specific genotype and the site of infection is crucial. Accordingly, the current study aimed at comparing predominant M.tb genotypes in pulmonary (PTB) and extrapulmonary tuberculosis (EPTB) isolates circulating in the capital of Iran. Methods: The genetic diversity of culture-confirmed PTB and EPTB isolates were evaluated by Spoligotyping and MIRU-VNTR (mycobacterial interspersed repetitive-unit–variable-number tandem-repeat) typing methods. Genotyping data were analyzed ... سال انتشار: 2019
 

Molecular investigation of virulence factors of Brucella melitensis and Brucella abortus strains isolated from clinical and non-clinical samples

مولف: Reza Mirnejad a, Faramarz Masjedian Jazi b, Shayan Mostafaei c, d, Mansour Sedighi

خلاصه: Brucella is zoonotic pathogen that induces abortion and sterility in domestic mammals and chronic infections in humans called Malta fever. It is a facultative intracellular potential pathogen with high infectivity. The virulence of Brucella is dependent upon its potential virulence factors such as enzymes and cell envelope associated virulence genes. The aim of this study was to investigate the Brucella virulence factors among strains isolated from humans and animals in different parts of Iran. ... سال انتشار: 2017
 

Association Study of CD226 and CD247 Genes Single Nucleotide Polymorphisms in Iranian Patients with Systemic Sclerosis

مولف: Fatemeh Abbasi1, Reza Mansouri1, Farhad Gharibdoost2, Saeed Aslani2, Shayan Mostafaei2, Hoda Kavosi2, Shiva Poursani2, Soheila Sobhani2, and Mahdi Mahmoudi2

خلاصه: CD247 and CD226 play important roles in signaling of lymphocytes. Single nucleotide polymorphisms (SNPs) of genes encoding CD247 and CD226 have been associated with the risk of several autoimmune disorders. This study aimed to evaluate the possible association between CD226 and CD247 genes SNPs and risk of systemic sclerosis (SSc) in Iranian population. Study participants were 455 SSc patients and 455 age, sex, and ethnic -matched healthy individuals. Genotyping of rs2056626 ... سال انتشار: 2017
 

Headache in Behcet’s disease: types and characteristics

Authers: Maryam Moghaddassi1, Mansoureh Togha2, 3*, Farhad Shahram1, Hamed Hanif4, Sahar Dadkhah5, Soodeh Razeghi Jahromi6 and Mohammad Mozafari2

Abstract: Behcet’s disease involves several systems in the body. Neurological involvement is identified by different symptoms. Headache is one of the common complaints of patients with Behcet’s disease. It might be a part of neurological involvement or may arise independently in the course of disease. Studies with small sample size have resulted in various findings in this field. Since the prevalence of Behcet’s disease is relatively high in Iran, this study was carried out to ... سال انتشار: 2016
 

Headache in Behcet’s disease: types and characteristics

Authers: Maryam Moghaddassi1, Mansoureh Togha2, 3*, Farhad Shahram1, Hamed Hanif4, Sahar Dadkhah5, Soodeh Razeghi Jahromi6 and Mohammad Mozafari2

Abstract: Behcet’s disease involves several systems in the body. Neurological involvement is identified by different symptoms. Headache is one of the common complaints of patients with Behcet’s disease. It might be a part of neurological involvement or may arise independently in the course of disease. Studies with small sample size have resulted in various findings in this field. Since the prevalence of Behcet’s disease is relatively high in Iran, this study was carried out to ... سال انتشار: 2016
 

Association of STAT4 rs7574865 with Susceptibility to Systemic Lupus Erythematosus in Iranian Population

Authers: Sedigheh Mirkazemi, 1 Mahmoud Akbarian, 2 Ahmad Reza Jamshidi, 2 Reza Mansouri, 3 Shima Ghoroghi, 2 Yahya Salimi, 4 Zahra Tahmasebi, 2 and Mahdi Mahmoudi2, 5

Abstract: Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease with complex genetic inheritance that affecting different organs and systems. STAT4 has been newly identified as a susceptible gene in the development of SLE. According to recent studies, STAT4 has been associated with SLE in various populations. We investigated whether STAT4 single nucleotide polymorphisms (SNPs) were associated with susceptibility and clinical features of SLE in Iranian patients. The study group comprised 280 patients with SLE and ... سال انتشار: 2013
 

Study of the correlation of serum selenium level with Behcet’s disease

Authers: Kamal ESALATMANESH, Ahmadreza JAMSHIDI, Farhad SHAHRAM, Fereydun DAVATCHI, Seyed Ali MASOUD, Zahra SOLEIMANI, Mansour SALESI, Iman GHAFFARPASAND

Abstract: Selenium, like other trace elements and antioxidant enzymes, is known as an antioxidant and immunomodulator trace element. Due to recent evidence for selenium deficiency in Behcet’s syndrome, this study is to evaluate the correlation of serum selenium level with Behcet’s disease (BD). Materials: This case–control study was conducted on 46 BD patients and 46 healthy controls in a rheumatology research centre. The case and control groups were both age- and race-matched. Serum selenium level ... سال انتشار: 2011
 

A WHO-ILAR COPCORD STUDY (Stage 1, rural study) IN IRAN

Authers: Davatchi, Fereydoun;, Tehran Banihashemi, Arash;, Gholami, Jaleh;, faezi, seyedeh tahereh;, Forouzanfar, Mohammad Hossein;, Salesi, Mansour, Karimifar, mansour, Essalat-Manesh, Kamal, Barghamdi, Mojgan, Noorolahzadeh, Elham, Dahaghin, Saideh

Abstract: Objective: To study the prevalence of musculoskeletal complaints and disorders in a rural area in Iran. Materials and Methods: Interviews were conducted in randomly selected subjects from 5 villages in Tuyserkan County, North Western part of Iran. The 3 phases of stage 1 COPCORD (Community Oriented Program for Control Of Rheumatic Diseases) were done during the same day. Results: A total of 614 houses was visited, 1565 persons interviewed and 1192 persons examined. Musculoskeletal complaints ... سال انتشار: 2009
 

The prevalence of musculoskeletal complaints in a rural area in Iran: a WHO-ILAR COPCORD study (stage 1, rural study) in Iran

Authers: Fereydoun Davatchi, Arash Tehrani Banihashemi, Jaleh Gholami, Seyedeh Tahereh Faezi, Mohammad Hossein Forouzanfar, Mansour Salesi, Mansour Karimifar, Kamal Essalatmanesh, Mojgan Barghamdi, Elham Noorolahzadeh, Saideh Dahaghin, Johannes J. Rasker

Abstract: The objective of this study is to study the prevalence of musculoskeletal complaints and disorders in a rural area in Iran. Interviews were conducted in randomly selected subjects from five villages in Tuyserkan County, northwestern part of Iran. The three phases of stage 1 Community Oriented Program for Control of Rheumatic Diseases were done during the same day. A total of 614 houses was visited, 1,565 persons interviewed, and 1,192 persons examined. Musculoskeletal complaints during the past 7 days ... سال انتشار: 2009
 

The Comparison of Serum Zinc Level in Behcet Patients and Healthy Controls

Authers: Kamal Esalatmanesh MD, Ahmadreza Jamshidi MD, Farhad Shahram MD, Fereydoun Davatchi MD, Zahra Soleimani MD, Shohreh Movahedi MD*****, , Mansour Salesi MD, Mansoor Karimifar MD

Abstract: Zinc was suggested as an antioxidant and immunomodulator trace element in parallel with other trace elements and antioxidant enzymes. Recently selenium deficiency was indicated in Behcet disease. In this study, we evaluated the correlation of serum zinc level and Behcet disease. Background: In a cross-sectional, descriptive study serum level of zinc was measured in 49 cases satisfying International Study Group criteria and 51 controls. Serum zinc level was measured by atomic absorption spectrometry and compared the mean of serum ... سال انتشار: 2009
 

Effect of ethnic origin (Caucasians versus Turks) on the prevalence of rheumatic diseases: a WHO-ILAR COPCORD urban study in Iran

Authers: Fereydoun Davatchi،Ahmad-Reza Jamshidi،Arash Tehrani Banihashemi،Jaleh Gholami،Mohammad Hossein Forouzanfar،Massoomeh Akhlaghi،Mojgan Barghamdi،Elham Noorolahzadeh،Ali-Reza Khabazi،Mansour Salesi،Amir-Hossein Salari،Mansoor Karimifar،Kamal Essalat-Manesh

Abstract: The objective of this study was to compare the prevalence of musculoskeletal complaints and rheumatic disorders in Caucasians and Turks in an identical environment. Subjects were selected randomly for an interview from Tehran’s 22 districts. The Community Oriented Program for Control of Rheumatic Diseases questionnaire was filled in, positive cases were examined, and if needed, laboratory or X-ray tests were performed. A total of 4,096 houses were visited, and 10,291 persons were interviewed. They were 71.4% Caucasians and 23.1% ... سال انتشار: 2009
 

The protein–creatinine ratio in spot morning urine samples and 24-h urinary protein excretion in patients with systemic lupus erythematosus

Authers: Mansour Salesi, Mansoor Karimifar, Ziba Farajzadegan, Kamal Esalatmanesh, Shahrzad Khosravi, Parvin Fallahi, Mahmood Akbarian

Abstract: A 24-h urinary protein is a standard way to diagnose lupus nephritis. Assessment of protein–creatinine (Pr–Cr) ratio in morning spot urine is a valuable method in diabetic patients but not use in systemic lupus erythematous (SLE) patients routinely. In this study Pr–Cr ratio in spot urine was compare with 24-h urine protein; if they have valuable correlation we can use this test instead of 24- h urinary protein. The aim of this study was to evaluate the correlation ... سال انتشار: 2008