تالیفات

Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients  

Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients

مولف: Parisa Zafari, Kheirollah Yari, Shayan Mostafaei, Nasrin Iranshahi, Shirin Assar, Adel Fekri & Mahdi Taghadosi

خلاصه: The control of auto-reactive cells is defective in rheumatoid arthritis (RA). Regulatory T (Treg) cells which play a key role in the modulation of immune responses have an impaired function in RA. Foxp3 is a master regulator of Treg cells which its expression is سال انتشار: 2018
 

The association of pathergy reaction and active clinical presentations of Behçet’s disease

مولف: Shirin Assar1, Bahar Sadeghi2, Fereydoun Davatchi2, Seyyedeh Zahra Ghodsi2, Abdolhadi Nadji2, Farhad Shahram2, Farimah Ashofte2, Seyyedeh Roghieh Larimi2, Masoud Sadeghi3

خلاصه: Objectives: The pathergy skin test is a hypersensitivity reaction to a prick skin trauma caused by a pin or a needle, which is considered as a specific presentation in Behçet’s disease (BD) and the precise mechanism of this test is not well elucidated. This study was designed to evaluate the association of pathergy reaction (PR) with the active clinical manifestations of BD patients, to assess the clinical importance of PR. Materials and methods: This was ... سال انتشار: 2017
 

Evaluation of PBMC Distribution and TLR9 Expression in Patients with Systemic Lupus Erythematosus

Authers: Sahar Mortezagholi1, Zohreh Babaloo1, Parisa Rahimzadeh2, Mojgan Ghaedi2, Hayedeh Namdari3, Shirin Assar4, Maryam Azimi Mohamadabadi5, and Eisa Salehi5

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease which results in damage to various organs. Some animal studies have revealed that activation of Toll-like receptors (TLRs) is important in the pathogenesis of SLE. In the present study, the percentage of different immune cell subsets in 35 SLE patients and 38 control subjects was analyzed by flow cytometry. We also assessed the expression of TLR9 in the population of peripheral blood ... سال انتشار: 2016