تالیفات

 

The association of pathergy reaction and active clinical presentations of Behçet’s disease

مولف: Shirin Assar1, Bahar Sadeghi2, Fereydoun Davatchi2, Seyyedeh Zahra Ghodsi2, Abdolhadi Nadji2, Farhad Shahram2, Farimah Ashofte2, Seyyedeh Roghieh Larimi2, Masoud Sadeghi3

خلاصه: Objectives: The pathergy skin test is a hypersensitivity reaction to a prick skin trauma caused by a pin or a needle, which is considered as a specific presentation in Behçet’s disease (BD) and the precise mechanism of this test is not well elucidated. This study was designed to evaluate the association of pathergy reaction (PR) with the active clinical manifestations of BD patients, to assess the clinical importance of PR. Materials and methods: This was ... سال انتشار: 2017
 

Prospective study of articular manifestations in Behcet’s disease: five-year report

Authers: Alimohammad FATEMI, 1, 2 Farhad SHAHRAM, 2 Massoomeh AKHLAGHI, 2 Abbas SMILEY, 3 Abdolhadi NADJI2 and Fereydoun DAVATCHI2

Abstract: Aim: To evaluate different aspects of articular involvements (prevalence, types, relation to extra-articular manifestations, etc.) in Iranian patients with Behcet’s disease (BD). Methods: In a prospective study, all patients with BD attending an outpatient BD clinic were enrolled. The type of articular involvements (peripheral or axial), involved joints, duration of attacks and their relation to extraarticular manifestations, human leukocyte antigen (HLA)-B5 and HLA-B27 were evaluated. Data analysis was done by using descriptive statistical indices such ... سال انتشار: 2015
 

The relationship between plasma homocysteine level and HLA-B51 in patients with Behcet’s disease: a case-control study

Authers: Soraya SHADMANFAR, 1, 2 Farhad SHAHRAM, 2 Abdolhadi NADJI, 2 Maassoumeh AKHLAGHI, 2 Seyedeh T. FAEZI, 2 Bahar SADEGHI-ABDOLLAHI, 2 Alireza FARIDAR, 2 Nima MADANCHI3 and Fereydoun DAVATCHI2

Abstract: Background: Various coagulation disorders have been reported to explain hypercoagulability state in Behcet’s disease (BD). A possible negative association between human leukocyte antigen (HLA)-B51 and increased homocysteine level has been suggested in a previous report from Iranian patients with BD. The aim of this study was to find any possible relationship between plasma homocysteine levels and HLA-B51. Methods: In a case-control study, BD patients (fulfilling the new International Criteria for BD) and controls (who had ... سال انتشار: 2014
 

Multiple Imputation to Deal with Missing Clinical Data in Rheumatologic Surveys: an Application in the WHO-ILAR COPCORD Study in Iran

Authers: M Mirmohammadkhani1, A Rahimi Foroushani1, F Davatchi2, 3, K Mohammad1, A Jamshidi2, 3, A Tehrani Banihashemi1, 3, *K Holakouie Naieni 1,

Abstract: The aim of the article is demonstrating an application of multiple imputation (MI) for handling missing clinical data in the setting of rheumatologic surveys using data derived from 10291 people participating in the first phase of the Community Oriented Program for Control of Rheumatic Disorders (COPCORD) in Iran. Methods: Five data subsets were produced from the original data set. Certain demographics were selected as complete variables. In each subset, we created a univariate pattern ... سال انتشار: 2012
 

Fc-Gamma Receptor 3B Copy Number Variation Is Not a Risk Factor for Behc¸et’sDisease

Authers: Rachel Black, 1 Sue Lester, 1 Emma Dunstan, 1 Farhad Shahram, 2 Abdolhadi Nadji, 2 Noushin Bayat, 2, 3 Kayvan Saeedfar, 2, 4 Naghmeh Ziaei, 2 Catherine Hill, 1, 5 Maureen Rischmueller, 1, 5 and Fereydoun Davatchi2

Abstract: Behc¸et’s disease (BD) is an immune-mediated systemic vasculitis associated with HLAB51. Other gene associations are likely and may provide further insight into the pathogenesis of this disease. Fc-gamma receptors play an important role in regulating immune function. Copy number variation (CNV) of the Fc-gamma receptor 3B (FCGR3B) gene is associated with other inflammatory conditions and may also play a role in BD. The aim of this study was to determine whether CNV of ... سال انتشار: 2012