Systemic lupus erythematosus in Iran, analysis of 156 cases.


Abstract: From 1975 to 1982, 156 patients with systemic lupus erythematosus were seen. 90 % were women, 69 % were aged between 10 to 30 years. 63 % had a deterioration of their general condition. Skin disorders was found in 92 % with 78 % of facial erythema, 46 % photosensitivity, 56 % Alopecia, 9 % Raynauds phenomenon and 19 % oral lesions. Osteoarticular changes were detected in 84 % renal involvement in 71 %, neuropsychiatric manifestations in 31 %, cardiac manifestations in 15 %, pleuro-pulmonar in 19 %, hepatic in 13 % and gastrointestinal disorders in 23 % Anemia was seen in 28 %, Leucopenia in 24 %, Thrombocytopenia in 12 % and LE cells in 56 % of the patients. Anti nuclear factors by immunofluorescence were positive in 75 % of patients while high anti native DNA was detected in 50 % of them.