RRC

Bio

Mahdi Mahmoudi (Ph.D) is associate professor of Immunology at Rheumatology Research Center (RRC), Tehran University of Medical Sciences (TUMS). Mahdi is vice dean for research and International affair of RRC. He is editorial manager of Rheumatology Research journal, the officially journal of Iranian Rheumatology Association (IRA). He is manager of cellular and molecular Immunology laboratory of RRC. He has a background on cellular and molecular (genetic) basis of autoimmune diseases especially autoimmune rheumatic diseases.

Mahdi has been principle investigator of more than 200 national and international collaborative research projects. He is also principle investigator of national registry for rheumatic diseases in collaboration with Ministry of Health and Medical Education. He has supervised more than 80 MSc and PhD students.

Research Focus

Immunogenetics of Autoimmune Rheumatic Diseases

Academic Appointments

Ph.D. of Immunology, Professor, Vice President of Rheumatology Research Center (RRC), Tehran University of Medical Sciences (TUMS),

Apply

Researches

Genetic of Ankylosing Spondylitis

PI: Mahdi Mahmoudi

Systemic Lupus Erythematosus (SLE) is an autoimmune multi-organ disorder that has thousands faces of presentations. Its clinical course is extremely unpredictable, and these features make its diagnosis and treatment a real challenge for clinicians. It appears that the clinical course of SLE is determined by the genetic material, in combination with environmental factors. In this article, we have reviewed recent findings on SLE pathogenesis with genetics view, focusing on defects in clearance of apoptotic bodies and immune complexes, alterations in innate immune system response, and also impaired pathways in the adaptive immune system. Furthermore, the major histocompatibility complex (MHC) and non-MHC genes that were discovered by genome-wide association studies (GWAS) in SLE patients were also evaluated. Besides, the effect of these polymorphisms on the function of their related transcripts and their association with SLE clinical manifestations and its pathophysiology were explained. Finally, the correlation of genetic polymorphisms with clinical responses to common medications in SLE treatment was also discussed.

Book Chapters

Pharmacoepigenetics

The Epigenetics of Autoimmunity

Pulmonary Manifestations of Primary Immunodeficiency Diseases

Papers

Attenuation of aquaporin‐3 and epidermal growth factor receptor expression and activation in systemic sclerosis dermal fibroblasts

E Farhadi, M Mahmoudi, F Rahmani, B Yousefi, A Sarafnejad, H Kavosi, ...

Journal of cellular physiology 234 (8), 12876-12883, 2019

Downregulation of Drosha, Dicer, and DGCR8 mRNAs in peripheral blood mononuclear cells of patients with rheumatoid arthritis

M Akhlaghi, S Soltani, F Jamshidi, ST Faezi, S Aslani, S Poursani, ...

Rheumatology Research 3 (4), 135-143, 2018

Association study between killer immunoglobulin‐like receptor polymorphisms and ankylosing spondylitis disease: An updated meta‐analysis

R Rezaei, S Mostafaei, S Aslani, A Jamshidi, M Mahmoudi

International journal of rheumatic diseases 21 (10), 1746-1755, 2018

Association of TYK2 rs34536443 polymorphism with Susceptibility to Systemic Lupus Erythematous in the Iranian Population

ST Faezi, S Soltani, M Akbarian, S Aslani, E Hamzeh, A Jamshidi, ...

Rheumatology Research 3 (4), 151-159, 2018

Histone variants expression in peripheral blood mononuclear cells of patients with rheumatoid arthritis

M Asadipour, V Hassan‐Zadeh, N Aryaeian, F Shahram, M Mahmoudi

International journal of rheumatic diseases 21 (10), 1831-1837, 2018

Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study

D González-Serna, E López-Isac, N Yilmaz, F Gharibdoost, A Jamshidi, ...

Rheumatology 58 (2), 289-298, 2018

HLA-B* 27 subtypes and their implications in the pathogenesis of ankylosing spondylitis

N Dashti, M Mahmoudi, S Aslani, A Jamshidi

Gene 670, 15-21, 2018

Increased inflammatory responsiveness of peripheral blood mononuclear cells (PBMCs) to in vitro NOD2 ligand stimulation in patients with ankylosing spondylitis

N Vanaki, T Golmohammadi, A Jamshidi, M Akhtari, M Vojdanian, ...

Immunopharmacology and immunotoxicology 40 (5), 393-400, 2018

Genetic Risk Score Prediction in Ankylosing Spondylitis

Z Li, E De Guzman, J Harris, N Akkoc, M Mahmoudi, M Breban, CT Chou, ...

ARTHRITIS & RHEUMATOLOGY 70, 2018

Association of IRF5 gene single nucleotide polymorphism with systemic lupus erythematosus susceptibility in Iranian population

F Ruhizadeh, V Imeni, SA Angaji, M Akbarian, T Faezi, A Jamshidi, ...

Gene Reports 12, 175-178, 2018

The role of killer-cell immunoglobulin-like receptor (KIR) genes in susceptibility to inflammatory bowel disease: systematic review and meta-analysis

A Fathollahi, S Aslani, S Mostafaei, N Rezaei, M Mahmoudi

Inflammation Research 67 (9), 727-736, 2018

Role of innate immune system in the pathogenesis of ankylosing spondylitis

N Vanaki, S Aslani, A Jamshidi, M Mahmoudi

Biomedicine & Pharmacotherapy 105, 130-143, 2018

Genetic implications in the pathogenesis of systemic sclerosis

R Rezaei, S Aslani, N Dashti, A Jamshidi, F Gharibdoost, M Mahmoudi

International journal of rheumatic diseases 21 (8), 1478-1486, 2018

Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with …

MT Palizgir, M Akhtari, M Mahmoudi, S Mostafaei, A Rezaiemanesh, ...

Immunopharmacology and immunotoxicology 40 (4), 297-302, 2018

Association between rs6759298 and Ankylosing Spondylitis in Iranian Population

M Mahmoudi, M Garshasbi, A Ashraf-Ganjouei, A Javinani, M Vojdanian, ...

Avicenna journal of medical biotechnology 10 (3), 178, 2018

THU0708 Disparity in osteoarthritis knee prevalence-a tale of two cities in iran (TEHRAN) and india (PUNE): findings from who ilar copcord population survey (STAGE I)

A Jamshidi, T Kianifard, R Ghorpade, M Shayan, M Mahmoudi, A Chopra

Annals of the Rheumatic Diseases 77 (Suppl 2), 546-546, 2018

A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-d-mannuronic acid in rheumatoid arthritis patients

H Ahmadi, AR Jamshidi, F Gharibdoost, M Mahmoudi, N Rastkari, ...

Inflammopharmacology 26 (3), 737-745, 2018

Association study between STAT4 polymorphisms and susceptibility to systemic lupus erythematosus disease: A systematic review and meta-analysis

H Ebrahimiyan, R Rezaei, S Mostafaei, S Aslani, GN Goulielmos, ...

Meta Gene 16, 241-247, 2018

Ankylosing spondylitis monocyte-derived macrophages express increased level of A2A adenosine receptor and decreased level of ectonucleoside triphosphate diphosphohydrolase-1 …

M Akhtari, SJ Zargar, M Mahmoudi, M Vojdanian, A Rezaeimanesh, ...

Clinical rheumatology 37 (6), 1589-1595, 2018

Expressions of p53 and PUMA in fibroblasts of systemic sclerosis patients are normal at transcription level

MB Mahmoudi, M Abed Khojasteh, F Alsahebfosoul, F Gharibdoost, ...

Journal of cosmetic dermatology 17 (3), 549-554, 2018

The Profile of Toll-like Receptor 2 (TLR2), TLR4 and Their Cytosolic Downstream Signaling Pathway in Common Variable Immunodeficiency (CVID) Patients

L Sharifi, A Aghamohammadi, N Rezaei, R Yazdani, M Mahmoudi, ...

Iranian Journal of Allergy, Asthma and Immunology 17 (2), 188-200, 2018

Genetic and epigenetic etiology of autoimmune diseases: lessons from twin studies

S Aslani, R Rezaei, A Jamshidi, M Mahmoudi

Rheumatology Research 3 (2), 45-57, 2018

The effects of β-d-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the …

F Jafarnezhad-Ansariha, MS Yekaninejad, A Jamshidi, R Mansouri, ...

Inflammopharmacology 26 (2), 375-384, 2018

Association of killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands with susceptibility to Behçet’s disease

H Mohammad-Ebrahim, E Kamali-Sarvestani, M Mahmoudi, M Beigy, ...

Scandinavian journal of rheumatology 47 (2), 155-163, 2018

Evaluation of ITGB2 (CD18) and SELL (CD62L) genes expression and methylation of ITGB2 promoter region in patients with systemic sclerosis

N Dashti, M Mahmoudi, F Gharibdoost, H Kavosi, R Rezaei, V Imeni, ...

Rheumatology international 38 (3), 489-498, 2018

Targeting of circulating Th17 cells by β-d-mannuronic acid (M2000) as a novel medication in patients with rheumatoid arthritis

H Ahmadi, M Mahmoudi, F Gharibdoost, M Vojdanian, A reza Jamshidi, ...

Inflammopharmacology 26 (1), 57-65, 2018

Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: a 12-week randomized, placebo-controlled, phase I/II clinical trial

MJ Fattahi, AR Jamshidi, M Mahmoudi, M Vojdanian, MS Yekaninejad, ...

International immunopharmacology 54, 112-117, 2018

Association of IL-23R gene rs7517847 T> G SNP and susceptibility to systemic lupus erythematosus: A systematic review and meta-analysis

D Imani, R Rezaei, A Poorsheikhani, S Alizadeh, M Mahmoudi

Rheumatology Research 3 (1), 13-20, 2018

Association study of CCR6 gene single nucleotide polymorphism with susceptibility to rheumatoid arthritis in Iranian population

Y Mohammadi Kebar, M Akhlaghi, Z Malekshahi, A Jamshidi, S Mostafaei, ...

Rheumatology Research 3 (1), 35-40, 2018

Evaluation of the association of single nucleotide polymorphisms in DDP4 and CDK5RAP2 genes with rheumatoid arthritis susceptibility in Iranian population

Z Malekshahi, M Mahmoudi, M Akhlaghi, M Garshasbi, A Jamshidi, ...

Egyptian Journal of Medical Human Genetics 19 (3), 185–189, 2018

Association Study of CD226 and CD247 Genes Single Nucleotide Polymorphisms in Iranian Patients with Systemic Sclerosis

F Abbasi, R Mansouri, F Gharibdoost, S Aslani, S Mostafaei, H Kavosi, ...

Iranian Journal of Allergy, Asthma and Immunology 16 (6), 471-479, 2017

Epigenetic involvement in etiopathogenesis and implications in treatment of systemic lupus erythematous

AM Foma, S Aslani, J Karami, A Jamshidi, M Mahmoudi

Inflammation Research 66 (12), 1057-1073, 2017

Association Study of MECP2 Gene Single Nucleotide Polymorphisms in Juvenile-Onset Systemic Lupus Erythematosus Patients from Iran

M Mahmoudi, S Aslani, E Hamzeh, V Ziaee, S Poursani, MH Nicknam, ...

Fetal and pediatric pathology 36 (6), 423-431, 2017

The potent suppressive effect of β-d-mannuronic acid (M2000) on molecular expression of the TLR/NF-kB Signaling Pathway in ankylosing spondylitis patients

M Roozbehkia, M Mahmoudi, S Aletaha, N Rezaei, MJ Fattahi, ...

International immunopharmacology 52, 191-196, 2017

Macrophages from Behcet's Disease Patients Express Decreased Level of Aryl Hydrocarbon Receptor (AHR) mRNA

MT Palizgir, M Akhtari, M Mahmoudi, S Mostafaei, A Rezaeimanesh, ...

Iranian Journal of Allergy, Asthma and Immunology 16 (5), 418-424, 2017

Hematological improvement of patients with active rheumatoid arthritis by β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property

H Ahmadi, AR Jamshidi, M Mahmoudi, F Gharibdoost, M Vojdanian, ...

Iranian Journal of Allergy, Asthma and Immunology 16 (5), 433-442, 2017

IRF 7 gene expression profile and methylation of its promoter region in patients with systemic sclerosis

R Rezaei, M Mahmoudi, F Gharibdoost, H Kavosi, N Dashti, V Imeni, ...

International journal of rheumatic diseases 20 (10), 1551-1561, 2017

Determination of ETS1 gene single nucleotide polymorphism in Iranian patients with ankylosing spondylitis

M Masoumi, M Mahmoudi, Z Malekshahi, J Karami, M Vojdanian, ...

Rheumatology Research 2 (4), 133-138, 2017

Ankylosing spondylitis M-CSF-derived macrophages are undergoing unfolded protein response (UPR) and express higher levels of interleukin-23

A Rezaiemanesh, M Mahmoudi, AA Amirzargar, M Vojdanian, ...

Modern rheumatology 27 (5), 862-867, 2017

Promoter hypermethylation of BCL11B gene correlates with downregulation of gene transcription in ankylosing spondylitis patients

J Karami, M Mahmoudi, A Amirzargar, M Gharshasbi, A Jamshidi, ...

Genes and immunity 18 (3), 170, 2017

The potent inhibitory effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on anti-cyclic citrullinated peptide antibodies, rheumatoid factor …

H Ahmadi, AR Jamshidi, M Mahmoudi, S Cuzzocrea, MJ Fattahi, A Barati, ...

Current drug discovery technologies 14 (3), 206-214, 2017

Association analysis of RAC1 single nucleotide polymorphisms with ulcerative colitis.

M Taher, DN Ebrahimi, M Hedayat, M Eslamian, E Farhadi, M Mahmoudi, ...

Clinics and research in hepatology and gastroenterology 41 (4), 487, 2017

Association Study between Single Nucleotide Polymorphisms of Vascular Endothelial Growth Factor and Risk of Breast Cancer Among Iranian Population

A Amirzargar, N Hamzavi, M Mahmoodi, M Mahmoudi, E Mohebbi, ...

Basic & Clinical Cancer Research 9 (1), 12-20, 2017

Analysis of killer cell immunoglobulin-like receptors (KIRs) and their HLA ligand genes polymorphisms in Iranian patients with systemic sclerosis

M Mahmoudi, F Fallahian, S Sobhani, S Ghoroghi, A Jamshidi, ...

Clinical rheumatology 36 (4), 853-862, 2017

New insights toward the pathogenesis of ankylosing spondylitis; genetic variations and epigenetic modifications

M Mahmoudi, S Aslani, MH Nicknam, J Karami, AR Jamshidi

Modern rheumatology 27 (2), 198-209, 2017

Association of STAT4 gene single nucleotide polymorphisms with Iranian juvenile-onset systemic lupus erythematosus patients

A Salmaninejad, M Mahmoudi, S Aslani, S Poursani, V Ziaee, N Rezaei

The Turkish journal of pediatrics 59 (2), 144-149, 2017

Prevalence and Clinical Investigation of the Behcet’s Disease in Middle East and North Africa: A Systematic Review and Meta-Analysis

M Palizgir, M Mahmoudi, M Qorbani, S Djalalinia, S Mostafaei, F Shahram

Iranian Red Crescent Medical Journal 19 (4), 2017

Inhibition of MicroRNA‐21 induces apoptosis in dermal fibroblasts of patients with systemic sclerosis

S Jafarinejad‐Farsangi, A Farazmand, F Gharibdoost, E Karimizadeh, ...

International journal of dermatology 55 (11), 1259-1267, 2016

Evaluation of DNMT1 gene expression profile and methylation of its promoter region in patients with ankylosing spondylitis

S Aslani, M Mahmoudi, M Garshasbi, AR Jamshidi, J Karami, ...

Clinical rheumatology 35 (11), 2723-2731, 2016

Lack of association between btb domain and cnc homolog 2 polymorphism and susceptibility to rheumatoid arthritis in Iranian population

Z Malekshahi, M Mahmoudi, M Akhlaghi, M Garshasbi, AR Jamshidi, ...

Indian Journal of Rheumatology 11 (4), 197, 2016

Analysis of killer cell immunoglobulin-like receptors and their human leukocyte antigen-ligands gene polymorphisms in Iranian patients with systemic lupus erythematosus

M Akhtari, A Farazmand, M Mahmoudi, M Akbarian, N Ahmadzadeh, ...

Lupus 25 (11), 1244-1253, 2016

Determination of IL1R2, ANTXR2, CARD9, and SNAPC4 single nucleotide polymorphisms in Iranian patients with ankylosing spondylitis

P Momenzadeh, M Mahmoudi, M Beigy, M Garshasbi, M Vodjdanian, ...

Rheumatology international 36 (3), 429-435, 2016

Epigenetic alterations underlying autoimmune diseases

S Aslani, M Mahmoudi, J Karami, AR Jamshidi, Z Malekshahi, ...

Autoimmunity 49 (2), 69-83, 2016

Analysis of killer cell immunoglobulin-like receptor genes and their HLA ligands in Iranian patients with ankylosing spondylitis

M Mahmoudi, AR Jamshidi, J Karami, A Mohseni, AA Amirzargar, ...

Iranian Journal of Allergy, Asthma and Immunology 15 (1), 27-38, 2016

Gene expression profiling of toll-like receptor 4 and 5 in peripheral blood mononuclear cells in rheumatic disorders: ankylosing spondylitis and rheumatoid arthritis

S Almasi, S Aslani, H Poormoghim, AR Jamshidi, S Poursani, ...

Iranian Journal of Allergy, Asthma and Immunology 15 (1), 87-92, 2016

Gene expression profiling of toll-like receptor 4 and 5 in peripheral blood mononuclear cells of patients with systemic sclerosis

S Almasi, S Aslani, H Poormoghim, A Jamshidi, S Poursani, M Mahmoudi

American Journal of Immunology 12 (1), 10-16, 2016

PADI4 Polymorphisms in Iranian Patients with Rheumatoid Arthritis.

E Shamsian, M Azarian, M Akhlaghi, M Samaei, AR Jamshidi, S Assar, ...

Acta reumatologica portuguesa 41 (4), 338-343, 2016

Rare Mediterranean Fever (MEFV) Gene Polymorphisms Are Associated with Ankylosing Spondylitis in Turkish and Iranian Population

Z Li, A Servet, H Yarkan, P Cetin, G Can, G Kenar, O Nuri Pamuk, ...

Association study of AFF1 gene polymorphism (rs340630) with Iranian systemic lupus erythematosus patients.

E Arabi, M Garshasbi, AR Jamshidi, R Khalesi, N Ahmadzadeh, ...

Acta reumatologica portuguesa 41 (1), 2016

Determination of the association of ETS1 and WDFY4 gene polymorphisms with systemic lupus erythematosus in an Iranian population

R Mansouri, M Mahmoudi, S Mirkazemi, MB Mahmoudi, E Karimizadeh, ...

Rheumatology Research 1 (1), 11-16, 2016

Association of HLA class II (DRB1, DQA1, DQB1) alleles and haplotypes with myasthenia gravis and its subgroups in the Iranian population

S Ehsan, A Amirzargar, MS Yekaninejad, M Mahmoudi, S Mehravar, ...

Journal of the neurological sciences 359 (1-2), 335-342, 2015

Determination of killer cell immunoglobulin-like receptors (KIR) and their hla-ligands genes variation in Iranian patients with systemic sclerosis

M MAHMOUDI, S SOBHANI, F FALLAHIAN, S GHOROGHI, A JAMSHIDI, ...

International Journal of Rheumatic Diseases 18, 2015

Interleukin-23 receptor single nucleotide polymorphisms in Crohn's disease.

VF Najmi, E Farhadi, DN Ebrahimi, M Taher, M Mahmoudi, M Bashashati, ...

Clinics and research in hepatology and gastroenterology 39 (4), e51, 2015

MicroRNA-29a induces apoptosis via increasing the Bax: Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis

S Jafarinejad-Farsangi, A Farazmand, M Mahmoudi, F Gharibdoost, ...

Autoimmunity 48 (6), 369-378, 2015

بررسی و تعیین اثرات متقابل مهم پلیمورفیسم های تک نوکلئوتیدی ژنهای سایتوکاینهای التهابی و ضد التهابی در ابتلا به بیماری لوپوس آریتماتوز سیستمیک با استفاده از رویکرد شناسه گزینی …

سعید مهرآور, S Mehravar, کرامت نوری جلیانی, K Nourijelyani, کمال اعظم, ...

مجله دانشگاه علوم پزشکی خراسان شمالی 6 (1), 2014

Evaluating the reliability of Persian version of ankylosing spondylitis quality of life (ASQoL) questionnaire and related clinical and demographic parameters in patients with …

S Fallahi, AR Jamshidi, K Bidad, M Qorbani, M Mahmoudi

Rheumatology international 34 (6), 803-809, 2014

Are clinical measures influenced by various ethnic origins in Iranian patients with ankylosing spondylitis? A pilot study

S Fallahi, AR Jamshidi, M Mahmoudi, M Qorbani

Caspian journal of internal medicine 5 (2), 59, 2014

Erratum to Interleukin-23 receptor single nucleotide polymorphisms with ulcerative colitis. A studying Iranian population [Clin. Res. Hepatol. Gastroenterol. 38 (2014) 360-5]

NE Daryani, FN Varzaneh, M Hedayat, M Taher, E Farhadi, M Mahmoudi, ...

Clinics and research in hepatology and gastroenterology 38 (4), 538-540, 2014

Association of STAT4 rs7574865 with susceptibility to systemic lupus erythematosus in Iranian population

S Mirkazemi, M Akbarian, AR Jamshidi, R Mansouri, S Ghoroghi, Y Salimi, ...

Inflammation 36 (6), 1548-1552, 2013

Interleukin-1 gene cluster and IL-1 receptor polymorphisms in Iranian patients with systemic lupus erythematosus

Z Tahmasebi, M Akbarian, S Mirkazemi, A Shahlaee, Z Alizadeh, ...

Rheumatology international 33 (10), 2591-2596, 2013

The correlation between pack-years of smoking and disease activity, quality of life, spinal mobility, and sacroiliitis grading in patients with ankylosing spondylitis/Ankilozan …

S Fallahi, AR Jamshidi, F Gharibdoost, M Mahmoudi, N Ahmadzadeh, ...

Turkish Journal of Rheumatology 28 (3), 181, 2013

Effect of all-transretinoic acid on Th17 and T regulatory cell subsets in patients with ankylosing spondylitis

K Bidad, E Salehi, A Jamshidi, AA Saboor-Yaraghi, M Oraei, A Meysamie, ...

The Journal of rheumatology 40 (4), 476-483, 2013

Comparison of the Th1, IFN-γ secreting cells and FoxP3 expression between patients with stable graft function and acute rejection post kidney transplantation.

B Nazari, A Amirzargar, B Nikbin, M Nafar, P Ahmadpour, B Einollahi, ...

Iranian Journal of Allergy, Asthma and Immunology, 262-268?, 2013

Effect of HLA-B* 27 and its subtypes on clinical manifestations and severity of ankylosing spondylitis in Iranian patients.

S Fallahi, M Mahmoudi, MH Nicknam, F Gharibdoost, E Farhadi, A Saei, ...

Iranian Journal of Allergy, Asthma and Immunology, 321-330, 2013

Association between the interleukin 6 genotype at position-174 and atopic dermatitis

M Gharagozlou, E Farhadi, M Khaledi, N Behniafard, S Sotoudeh, ...

J Investig Allergol Clin Immunol 23 (2), 89-93, 2013

Evaluation of the Iranian versions of the bath ankylosing spondylitis disease activity index (BASDAI), the bath ankylosing spondylitis functional index (BASFI) and the patient …

K Bidad, S Fallahi, M Mahmoudi, A Jamshidi, E Farhadi, A Meysamie, ...

Rheumatology international 32 (11), 3613-3618, 2012

CORRELATION BETWEEN SCL-70 AUTOANTIBODY AND CLINICAL MANIFESTATION OF SCLERODERMA IN IRANIAN PATIENTS

B Nazari, M Gharibdoost, B Nazari, M Mahmoudi, AR Jamshidi, ...

RHEUMATOLOGY 51, 121-121, 2012

Coronary artery disease risk factors in an urban and peri-urban setting, Kerman, Southeastern Iran (KERCADR study): methodology and preliminary report

H Najafipour, A Mirzazadeh, AA Haghdoost, M Shadkam, M Afshari, ...

Iranian journal of public health 41 (9), 86, 2012

Association between endoplasmic reticulum aminopeptidase-1 (ERAP-1) and susceptibility to ankylosing spondylitis in Iran.

M Mahmoudi, AR Jamshidi, AA Amirzargar, E Farhadi, K Nourijelyani, ...

Iranian Journal of Allergy, Asthma and Immunology, 294-300, 2012

Graves' ophthalmopathy and gene polymorphisms in interleukin‐1α, interleukin‐1β, interleukin‐1 receptor and interleukin‐1 receptor antagonist

O Khalilzadeh, M Anvari, A Esteghamati, M Mahmoudi, M Tahvildari, ...

Clinical & experimental ophthalmology 37 (6), 614-619, 2009

HLA-B27 subtypes and tumor necrosis factor α promoter region polymorphism in Iranian patients with ankylosing spondylitis

MH Nicknam, M Mahmoudi, AA Amirzargar, AR Jamshidi, N Rezaei, ...

European cytokine network 20 (1), 17-20, 2009

Ankilozan Spondilit Hastalarında Sigara Paket Yılı ve Hastalık Aktivitesi, Yaşam Kalitesi, Spinal Mobilite ve Sakroileit Derecelendirmesi Arasındaki İlişki

S FALLAHI, AR JAMSHIDI, F GHARIBDOOST, M MAHMOUDI, ...

Effect of food intake and ambient air pollution exposure on ankylosing spondylitis disease activity

N Soleimanifar, MH Nicknam, K Bidad, AR Jamshidi, M Mahmoudi, ...

Advances in Rheumatology 59 (1), 9, 2019

Association study between KIR polymorphisms and rheumatoid arthritis disease: an updated meta-analysis

H Aghaei, S Mostafaei, S Aslani, A Jamshidi, M Mahmoudi

BMC medical genetics 20 (1), 24, 2019

Association between CD247 gene rs2056626 polymorphism and the risk of systemic sclerosis: Evidence from a systematic review and Bayesian hierarchical meta-analysis

N Vanaki, H Kavosi, S Aslani, S Mostafaei, P Riahi, F Gharibdoost, ...

Meta Gene, 100613, 2019

Study of vascular endothelial growth factor A gene polymorphisms in association with Iranian rheumatoid arthritis patients

M Mahmoodi, S Sobhani, M Akhlaghi, S Poursani, A Jamshidi, ...

Meta Gene 21, 100581, 2019

The safety and efficacy of Guluronic acid (G2013) in ankylosing spondylitis: A randomized controlled parallel clinical trial

S Nazeri, AR Jamshidi, M Mahmoudi, M Vojdanian, SK Azarian, S Afraei, ...

Pharmacological Reports 71 (3), 393-398, 2019

MicroRNA-21 and microRNA-29a modulate the expression of collagen in dermal fibroblasts of patients with systemic sclerosis

S Jafarinejad-Farsangi, F Gharibdoost, A Farazmand, H Kavosi, ...

Autoimmunity, 1-9, 2019

The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active Rheumatoid Arthritis

N Aryaeian, F Shahram, M Mahmoudi, H Tavakoli, B Yousefi, T Arablou, ...

Gene 698, 179-185, 2019

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis

Z Li, S Akar, H Yarkan, SK Lee, P Çetin, G Can, G Kenar, F Çapa, ...

PLoS genetics 15 (4), e1008038, 2019

Single Nucleotide Polymorphism of TYK2 Gene and Susceptibility to Rheumatoid Arthritis in Iranian Population

A Mohamadhosseini, R Mansouri, A Javinani, AA Ganjouei, M Akhlaghi, ...

Avicenna journal of medical biotechnology 11 (2), 187, 2019

Exploring the etiopathogenesis of systemic lupus erythematosus: a genetic perspective

A Javinani, A Ashraf-Ganjouei, S Aslani, A Jamshidi, M Mahmoudi

Immunogenetics 71 (4), 283-297, 2019

Are genetic variations in IL‐21–IL‐23R–IL‐17A cytokine axis involved in a pathogenic pathway of rheumatoid arthritis? Bayesian hierarchical meta‐analysis

FS Mohammadi, S Aslani, S Mostafaei, A Jamshidi, P Riahi, M Mahmoudi

Journal of cellular physiology, 2019

Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review

J Karami, S Aslani, A Jamshidi, M Garshasbi, M Mahmoudi

Gene, 2019

microRNA involvement in the regulation of survivin in peripheral blood mononuclear cells from rheumatoid arthritis patients

H Ebrahimiyan, N Rezaei, M Vojdanian, S Aslani, A Jamshidi, ...

International journal of rheumatic diseases, 2019

Association Study of Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 and 2 Genes in Iranian Women with Preeclampsia

H Dargahi, MH NICKNAM, M Mirahmadian, M Mahmoudi, S Aslani, ...

Iranian Journal of Public Health 48 (3), 531, 2019

Studying the Association between STAT4 Gene Polymorphism and Susceptibility to Rheumatoid Arthritis Disease: An Updated Meta-Analysis

H Ebrahimiyan, S Mostafaei, S Aslani, A Jamshidi, M Mahmoudi

Iranian journal of immunology: IJI 16 (1), 71-83, 2019

Overexpression of apoptosis-related protein, survivin, in fibroblasts from patients with systemic sclerosis

MB Mahmoudi, EF Yazd, F Gharibdoost, MH Sheikhha, E Karimizadeh, ...

Irish Journal of Medical Science (1971-), 1-7, 2019

A randomized clinical trial for the assessment of the efficacy and safety of guluronic acid (G2013) in patients with rheumatoid arthritis

SK Azarian, M Akhlaghi, M Mahmoudi, S Mostafaei, AR Jamshidi, ...

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 41 (1), 95-101, 2019

Pharmacoepigenetics of Immunological Disorders

R Rezaei, S Aslani, M Mahmoudi

Pharmacoepigenetics, 573-586, 2019

Pulmonary Manifestations of Autoinflammatory Disorders

A Jamshidi, S Aslani, M Mahmoudi

Pulmonary Manifestations of Primary Immunodeficiency Diseases, 193-211, 2019

Downregulation of miR-542-3p contributes to apoptosis resistance in dermal fibroblasts from systemic sclerosis patients via Survivin overexpression

PV Manesh, A Farazmand, F Gharibdoost, N Vanaki, S Mostafaei, ...

Iranian Journal of Allergy, Asthma and Immunology, 1-9, 2018

Activation of adenosine A2A receptor induced interleukin-23 mRNA expression in macrophages of ankylosing spondylitis patients

M Akhtari, M Vojdanian, A Javinani, A Ashraf-Ganjouei, A Jamshidi, ...

Cytokine 128, 154997, 2020

Epigenetics in rheumatoid arthritis; fibroblast‐like synoviocytes as an emerging paradigm in the pathogenesis of the disease

J Karami, S Aslani, MN Tahmasebi, MJ Mousavi, A Sharafat Vaziri, ...

Immunology and Cell Biology 98 (3), 171-186, 2020

P2 receptors mRNA expression profiles in macrophages from ankylosing spondylitis patients and healthy individuals

M Akhtari, SJ Zargar, M Vojdanian, A Ashraf‐Ganjouei, A Javinani, ...

International Journal of Rheumatic Diseases 23 (3), 350-357, 2020

Thanks to Our Peer-Reviewers in 2019

A Ajami, G Mosayebi, M Ghafourian, A Sheikhi, G Solgi, M Moghtaderi, ...

Iran. J. Immunol 17 (1), 94, 2020

ERAP1 polymorphisms interactions and their association with Behçet’s disease susceptibly: Application of Model-Based Multifactor Dimension Reduction Algorithm (MB-MDR)

P Riahi, A Kazemnejad, S Mostafaei, A Meguro, N Mizuki, ...

PloS one 15 (2), e0227997, 2020

Identification of RELN variant p.(Ser2486Gly) in an Iranian family with ankylosing spondylitis; the first association of RELN and AS

M Garshasbi, M Mahmoudi, E Razmara, M Vojdanian, S Aslani, E Farhadi, ...

European Journal of Human Genetics, 1-9, 2020

Association of Vascular Endothelial Growth Factor A gene polymorphisms with susceptibility to Systemic lupus erythematosus in Iranian population

M Mahmoudi, S Soltani, S Aslani, ST Faezi, A Jamshidi, E Farhadi

Rheumatology Research, 2019

Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

E Karimizadeh, A Sharifi-Zarchi, H Nikaein, S Salehi, B Salamatian, ...

BMC Medical Genomics 12 (1), 1-12, 2019

The Effects of Resveratrol on Oxidative Stress Markers: A Systematic Review and Meta-Analysis on Randomized Clinical Trials.

M Omidian, M Abdolahi, E Daneshzad, M Sedighiyan, M Aghasi, ...

Endocrine, metabolic & immune disorders drug targets, 2019

HLA class II polymorphism contribution to disease severity and response to treatment in myasthenia gravis

F Sinaei, S Nafissi, F Fatehi, SO Gharan, S Ehsan, K Kamali, M Mahmoudi

Journal of the Neurological Sciences 405, 314, 2019

Epigenetics in rheumatoid arthritis; fibroblast-like synoviocytes as an emerging paradigm in the pathogenesis of the disease.

J Karami, S Aslani, MN Tahmasebi, MJ Mousavi, A Sharafat Vaziri, ...

Immunol. cell biol, 2019

Epigenetic biomarkers of asthma and allergic disorders

M Akhtari, M Mahmoudi

Prognostic Epigenetics, 139-169, 2019

The effect of ginger supplementation on IL2, TNFα, and IL1β cytokines gene expression levels in patients with active rheumatoid arthritis: A randomized controlled trial

N Aryaeian, M Mahmoudi, F Shahram, S Poursani, F Jamshidi, H Tavakoli

Medical Journal of the Islamic Republic of Iran 33, 154, 2019

Epigenetics of autoimmune diseases

E Farhadi, M Mahmoudi

Prognostic Epigenetics, 203-244, 2019

Expression levels of the microRNA maturing microprocessor complex components; Drosha, Dicer, and DGCR8 in PBMCs from ankylosing spondylitis patients

Z Tabrizi, R Mansouri, S Aslani, AR Jamshidi, M Mahmoudi

Mediterranean Journal of Rheumatology 28 (2), 80-5, 2017

Association study of vascular endothelial growth factor gene polymorphisms with breast cancer risk in female patients

A Amirzargar, N Hamzavi, M Mahmoodi, M Mahmoudi, K Zendehdel, ...

Цитология и генетика 51 (6), 78-80, 2017

Expression of proinflammatory cytokines IL-17, IL-1B, TNF-A, IFN-Γ in Iranian patients with ankylosing spondylitis and their correlation with disease activity: APL15-0160

M ASADBEK, A FARAZMAND, A JAMSHIDI, M AMOLI, Z TABRIZI, F VAEZ, ...

International Journal of Rheumatic Diseases 18, 2015

Analysis of the gene expression of sulf1 and SULF2 in fibroblasts of the skin biopsy of patients with systemic sclerosis: APL15-0159

M MAHMOUDI, E FARASHAHI, A JAMSHIDI, E KARIMIZADEH, ...

International Journal of Rheumatic Diseases 18, 2015

Expression of IL-4 and TGF-B in Iranian patients with ankylosing spondylitis and their relation with disease activity: APL15-0161

F VAEZ, M MAHMOUDI, A FARAZMAND, Z TABRIZI, M ASADBEK, ...

International Journal of Rheumatic Diseases 18, 2015

Determination of killer cell immunoglobulin-like receptors (KIR) and their hla-ligands genes variation in Iranian patients with systemic sclerosis: APL15-0157

M MAHMOUDI, S SOBHANI, F FALLAHIAN, S GHOROGHI, A JAMSHIDI, ...

International Journal of Rheumatic Diseases 18, 2015

Identification of SNP interactions of inflammatory cytokines and anti-inflammatory genes in Systemic lupus erythmatosus’s disease using logic feature selection

S Mehravar, K Nourijelyani, K Azam, A Rahimi Foroushani, M Mahmoudi, ...

Journal of North Khorasan University of Medical Sciences 6 (1), 179-186, 2014

Comparison of the Th1, IFN-[gamma] secreting cells and FoxP3 expression between patients with stable graft function and acute rejection post kidney transplantation

B Nazari, A Amirzargar, B Nikbin, M Nafar, P Ahmadpour, B Einollahi, ...

Iranian Journal of Allergy, Asthma and Immunology 12 (3), 262, 2013

Erratum to ‘‘Interleukin-23 receptor single nucleotide polymorphisms with ulcerative colitis. A studying Iranian population’’[Clin. Res. Hepatol. Gastroenterol.

NE Daryani, FN Varzaneh, M Hedayat, M Taher, E Farhadi, M Mahmoudi, ...

The Effects of Resveratrol on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

M Omidian, M Abdolahi, E Daneshzad, M Sedighiyan, M Aghasi, ...

Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug …, 2020

Epigenetics in rheumatoid arthritis; fibroblast-like synoviocytes as an emerging paradigm in the disease pathogenesis.

J Karami, S Aslani, MN Tahmasebi, MJ Mousavi, VA Sherafat, A Jamshidi, ...

Immunology and cell biology, 2019

Dendritic Cells Currently under the Spotlight; Classification and Subset Based upon New Markers

S Soltani, M Mahmoudi, E Farhadi

Immunological Investigations, 1-16, 2020

Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study

H Aghaei, E Farhadi, M Akhtari, S Shahba, S Mostafaei, A Jamshidi, ...

BMC Medical Genetics 21 (1), 1-8, 2020

Interleukin-23 receptor single nucleotide polymorphisms with ulcerative colitis. A studying Iranian population (vol 38, pg 360, 2014)

NE Daryani, FN Varzaneh, M Hedayat, M Taher, E Farhadi, M Mahmoudi, ...

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY 38 (4), 538-540, 2014

The Effects of Hydroalcoholic Extract from Alhagi on Matrix Metalloproteinase-9 Production in Peripheral Blood Mononuclear Cells from Patients with Rheumatoid Arthritis

M Ahmadi, R Ebrahimi, M Ansari, M Akhlaghi, M Mahmoudi, G Amin, ...

The Natural Products Journal 10 (4), 440-445, 2020

Identification of novel variants in Iranian consanguineous pedigrees with nonsyndromic hearing loss by next‐generation sequencing

F Bitarafan, SY Seyedena, M Mahmoudi, M Garshasbi

Journal of Clinical Laboratory Analysis, e23544, 0

The effect of black barberry hydroalcoholic extract on immune mediators in patients with active rheumatoid arthritis: A randomized, double–blind, controlled clinical trial

N Aryaeian, M Hadidi, M Mahmoudi, M Asgari, ZS Hezaveh, SK Sadehi

Phytotherapy Research, 0

Intravenous methylprednisolone pulse as a treatment for hospitalised severe COVID-19 patients: results from a randomised controlled clinical trial

M Edalatifard, M Akhtari, M Salehi, Z Naderi, A Jamshidi, S Mostafaei, ...

European Respiratory Journal, 2020

In vitroEffect of oxLDL and PHA on Lymphocyte Proliferation/Cytotoxicity and Interleukin-2 Production in Patients with Atherosclerosis

M Mahmoudi, F Siassi, MJ Mahmoudi, F Shokri, M Eshraghian, A Zarnani, ...

Journal of Allergy and Clinical Immunology 127 (2), AB232, 2011

Assessment of the fungal flora and the prevalence of fungal infections in the mouth of diabetics

SH Yar Ahmadi, AR Khosravi, B Larijani, M Baiat, M Mahmoudi, ...

Iranian Journal of Endocrinology and Metabolism 4 (2), 105-109, 2002

Screening for microalbuminuria in the early detection of diabetic nephropathy: a cheap and simple method

B Larijani, A Javadi, A Shafaee, M Mahmoudi, P Hemati

Acta medica iranica, 65-68, 2002

Distinctive Expression of Bone Metabolism-related Genes between PBMCs from Condylar Hyperplasia, Rheumatoid Arthritis, and Ankylosing Spondylitis Patients

R Amirzargar, G Shirani, S Raisian, M Davoudi, S Aslani, S Poursani, ...

Iranian Journal of Allergy, Asthma and Immunology, 1-6, 2020

Evaluation of exercise test variables in diagnosis and prediction of the severity of coronary artery disease by fuzzy discriminant analysis

TRA MOHAMMADPOUR, GR BABAEE, M MAHMOUDI, A Memariani, ...

Journal of Mazandaran University of Medical Sciences 11 (33), 39-45, 2002

Effects of hydroalcoholic extract of Berberis integerrima on the clinical signs, hs-CRP, TNFα, and ESR in active rheumatoid arthritis patients

S Khorshidi-Sedehi, N Aryaeian, F Shahram, M Akhlaghi, M Mahmoudi, ...

Journal of Herbal Medicine 28, 100444, 2021

Association of HLA Class II Alleles with Disease Severity and Treatment Response in Iranian Patients with Myasthenia Gravis

F Sinaei, F Fatehi, S Oveis Gharan, S Ehsan, K Kamali, A Amirzargar, ...

Journal of Neuromuscular Diseases, 1-3, 2021

The p53 status in rheumatoid arthritis with focus on fibroblast-like synoviocytes

M Taghadosi, M Adib, A Jamshidi, M Mahmoudi, E Farhadi

Immunologic research, 1-14, 2021

Upmodulation of Unfolded Protein Response and ER Stress-Related IL-23 Production in M1 Macrophages From Ankylosing Spondylitis Patients

A Rezaiemanesh, M Mahmoudi, AA Amirzargar, M Vojdanian, F Babaie, ...

Co-expression Network Analysis Reveals Key Genes Related to Ankylosing spondylitis Arthritis Disease: Computational and Experimental Validation

L Najafzadeh, M Mahmoudi, M Ebadi, M Dehghan Shasaltaneh, ...

Iranian Journal of Biotechnology 19 (1), 74-85, 2021

Characterization of Occult Hepatitis B Virus Infection Among Iranian Patients with Behcet's Disease; Correlation with Clinical Status

F Shahram, S Ghorbani, M Mahmoudi, M Akhlaghi, Z Jadali, V Imeni, ...

Hepatitis Monthly 21 (1), 2021

The role of self-efficacy, pain catastrophizing, and fear of movement on chronic pain adjustment of rheumatoid arthritis patients

MB Soltanahmadi, M Akhlaghi, S mohammad Zahedi, M Mahmoudi, ...

Pain 11 (4), 80-93, 2021

microRNAs are potentially regulating the survivin gene in PBMCs from systemic sclerosis patients

H Ebrahimiyan, F Gharibdoost, S Aslani, H Kavosi, F Farsad, A Jamshidi, ...

Modern rheumatology 30 (5), 862-869, 2020

Finite Element Analysis of Metals Fatigue Damage, Based on Thermodynamic Entropy models

F Asnaashari, SH Dibajian, M Mahmoudi

Modares Mechanical Engineering 20 (5), 1361-1373, 2020

Antifungal activity of lactic acid bacteria isolated from Masske, camel dough, and local yogurt against Aspergillus flavus and Aspergillus niger

A Nasrollahzadeh, M Khomeiri, A Sadeghi, M Mahmoudi, M Ebrahimi

Food Hygiene 9 (4 (36)), 1-11, 2020

Using Multilevel Model to Investigate Factors Affecting on Intention to Stay of Young People in Villages (Case Study: The Selected Cities of Kermanshah Province)

M Mahmoudi, M Daneshvar Kakhki, N Shahnoushi, H Mohammadi

Journal of Economic Research (Tahghighat-E-Eghtesadi) 54 (3), 695-737, 2019

Investigation of Factors Affecting Conclusion and Implementation on Agricultural Contracts (Switching Regression Approach)

M MAHMOUDI, A KARBASI

AGRICULTURAL ECONOMICS: IRANIAN JOURNAL OF AGRICULTURAL ECONOMICS (ECONOMICS …, 2019

Investigating factors affecting on conclusion and implementation in agricultural contracts (approach switching regression).

M Mahmoudi, A Karbasi

Agricultural Economics (Karaj) 13 (3), 2019

Investigating the Role of Variables Affecting the Legatum Prosperity Index Using Ordered Logit Regression approach

H Mohammadi, M Mahmoudi

Journal Of Economics and Regional Development 25 (15), 1-20, 2018

The ability of the emergency medical service Personnel to take patients’ medical history

A Sadrollahi, A Gharataghani, M Mahmoudi, F Gholipour

Journal of Emergency Practice and Trauma 4 (2), 55-61, 2018

Ankylosing spondylitis monocyte-derived macrophages express increased level of A 2A adenosine receptor and decreased level of ectonucleoside triphosphate diphosphohydrolase-1 …

M Akhtari, SJ Zargar, M Mahmoudi, M Vojdanian, A Rezaeimanesh, ...

Clinical rheumatology 37 (6), 1589-1595, 2018

The effects of β-d-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte …

F Jafarnezhad-Ansariha, MS Yekaninejad, A Jamshidi, R Mansouri, ...

Inflammopharmacology 26 (2), 375-384, 2018

Mahdi Mahmoudi

Bio

Research Focus

Academic Appointments

Apply

Researches

PI: Mahdi Mahmoudi

Book Chapters

Pharmacoepigenetics

The Epigenetics of Autoimmunity

Pulmonary Manifestations of Primary Immunodeficiency Diseases

Papers

Attenuation of aquaporin‐3 and epidermal growth factor receptor expression and activation in systemic sclerosis dermal fibroblasts

Association study of copy number variation in BMP8A gene with the risk of ankylosing spondylitis in Iranian population

Implications of the noncoding RNAs in rheumatoid arthritis pathogenesis

Epistatic Interaction of ERAP1 and HLA-B* 51 in Iranian Patients with Behçet’s Disease

IL27 gene single nucleotide polymorphisms confer susceptibility to rheumatoid arthritis in Iranian population

Downregulation of Drosha, Dicer, and DGCR8 mRNAs in peripheral blood mononuclear cells of patients with rheumatoid arthritis

Association study between killer immunoglobulin‐like receptor polymorphisms and ankylosing spondylitis disease: An updated meta‐analysis

Association of TYK2 rs34536443 polymorphism with Susceptibility to Systemic Lupus Erythematous in the Iranian Population

Histone variants expression in peripheral blood mononuclear cells of patients with rheumatoid arthritis

Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study

HLA-B* 27 subtypes and their implications in the pathogenesis of ankylosing spondylitis

Increased inflammatory responsiveness of peripheral blood mononuclear cells (PBMCs) to in vitro NOD2 ligand stimulation in patients with ankylosing spondylitis

Genetic Risk Score Prediction in Ankylosing Spondylitis

Association of IRF5 gene single nucleotide polymorphism with systemic lupus erythematosus susceptibility in Iranian population

The role of killer-cell immunoglobulin-like receptor (KIR) genes in susceptibility to inflammatory bowel disease: systematic review and meta-analysis

Role of innate immune system in the pathogenesis of ankylosing spondylitis

Genetic implications in the pathogenesis of systemic sclerosis

Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with …

Association between rs6759298 and Ankylosing Spondylitis in Iranian Population

THU0708 Disparity in osteoarthritis knee prevalence-a tale of two cities in iran (TEHRAN) and india (PUNE): findings from who ilar copcord population survey (STAGE I)

A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-d-mannuronic acid in rheumatoid arthritis patients

Association study between STAT4 polymorphisms and susceptibility to systemic lupus erythematosus disease: A systematic review and meta-analysis

Ankylosing spondylitis monocyte-derived macrophages express increased level of A2A adenosine receptor and decreased level of ectonucleoside triphosphate diphosphohydrolase-1 …

Expressions of p53 and PUMA in fibroblasts of systemic sclerosis patients are normal at transcription level

The Profile of Toll-like Receptor 2 (TLR2), TLR4 and Their Cytosolic Downstream Signaling Pathway in Common Variable Immunodeficiency (CVID) Patients

Genetic and epigenetic etiology of autoimmune diseases: lessons from twin studies

The effects of β-d-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the …

Association of killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands with susceptibility to Behçet’s disease

Evaluation of ITGB2 (CD18) and SELL (CD62L) genes expression and methylation of ITGB2 promoter region in patients with systemic sclerosis

Epigenetics and pathogenesis of systemic sclerosis; the ins and outs

Multi-objective micro-grid design by NSGA-II considering both islanded and grid-connected modes

Single nucleotide polymorphism of Methyl-CpG-binding protein 2 gene associates with juvenile idiopathic arthritis

Targeting of circulating Th17 cells by β-d-mannuronic acid (M2000) as a novel medication in patients with rheumatoid arthritis

EFFECT OF FOOD INTAKE AND AMBIENT PARTICULATE AIR POLLUTION ON ANKYLOSING SPONDYLITIS DISEASE ACTIVITY

Future Challenges and Prospects for the Epigenetics of Autoimmunity

HBV reactivation in rheumatic diseases patients under therapy: A meta-analysis

Downregulation of Autophagy-Related Genes in Macrophages From Patients With Behcet’s Disease

Survivin and autoimmunity; the ins and outs

Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: a 12-week randomized, placebo-controlled, phase I/II clinical trial

Association of IL-23R gene rs7517847 T> G SNP and susceptibility to systemic lupus erythematosus: A systematic review and meta-analysis

Association study of CCR6 gene single nucleotide polymorphism with susceptibility to rheumatoid arthritis in Iranian population

Evaluation of the association of single nucleotide polymorphisms in DDP4 and CDK5RAP2 genes with rheumatoid arthritis susceptibility in Iranian population

Association Study of CD226 and CD247 Genes Single Nucleotide Polymorphisms in Iranian Patients with Systemic Sclerosis

Epigenetic involvement in etiopathogenesis and implications in treatment of systemic lupus erythematous

Association Study of MECP2 Gene Single Nucleotide Polymorphisms in Juvenile-Onset Systemic Lupus Erythematosus Patients from Iran

The potent suppressive effect of β-d-mannuronic acid (M2000) on molecular expression of the TLR/NF-kB Signaling Pathway in ankylosing spondylitis patients

Macrophages from Behcet's Disease Patients Express Decreased Level of Aryl Hydrocarbon Receptor (AHR) mRNA

Hematological improvement of patients with active rheumatoid arthritis by β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property

IRF 7 gene expression profile and methylation of its promoter region in patients with systemic sclerosis

Determination of ETS1 gene single nucleotide polymorphism in Iranian patients with ankylosing spondylitis

Ankylosing spondylitis M-CSF-derived macrophages are undergoing unfolded protein response (UPR) and express higher levels of interleukin-23

Promoter hypermethylation of BCL11B gene correlates with downregulation of gene transcription in ankylosing spondylitis patients

The potent inhibitory effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on anti-cyclic citrullinated peptide antibodies, rheumatoid factor …

Association analysis of RAC1 single nucleotide polymorphisms with ulcerative colitis.

Association Study between Single Nucleotide Polymorphisms of Vascular Endothelial Growth Factor and Risk of Breast Cancer Among Iranian Population

Downregulation of Aquaporin3 in systemic sclerosis dermal fibroblasts

Lack of Association between STAT4 Single Nucleotide Polymorphisms and Iranian Juvenile Rheumatoid Arthritis Patients

Upregulation of transforming growth factor-B1 gene in ankylosing spondylitis patients

The Anti-Migraine Effects of M2000 (β-D-Mannuronic Acid) on a Patient with Rheumatoid Arthritis: Case Report

Analysis of killer cell immunoglobulin-like receptors (KIRs) and their HLA ligand genes polymorphisms in Iranian patients with systemic sclerosis

New insights toward the pathogenesis of ankylosing spondylitis; genetic variations and epigenetic modifications

Association of STAT4 gene single nucleotide polymorphisms with Iranian juvenile-onset systemic lupus erythematosus patients

New insights to the mechanisms underlying atherosclerosis in rheumatoid arthritis

M2000 (β‐D‐Mannuronic Acid) as a Novel Antagonist for Blocking the TLR2 and TLR4 Downstream Signalling Pathway

PDCD1 Single Nucleotide Polymorphisms in Iranian Patients With Juvenile Idiopathic Arthritis

Association Between IL6-174 G/C Polymorphism and Graves' Disease: A Systematic Review and Meta-Analysis

Association study of vascular endothelial growth factor gene polymorphisms with breast cancer risk in female patients].

Gene expression profile of proinflammatory cytokines in Iranian patients with ankylosing spondylitis